ATRA

网络释义：全反式维甲酸(all-trans retinoic acid)；全反式视黄酸；自动变速器再造协会(Automatic Transmission Rebuilders Association)

网络释义

1.全反式维甲酸(all-trans retinoic acid)观察 龚维舜鲁厚清【摘要】：正国内自1986年开展全反式维甲酸(ATRA)治疗白血病以来,临床资料已经表明,ATRA治疗急性早 …

2.全反式视黄酸

4.全反维甲酸　　全反维甲酸(ATRA)是体内具有重要生理活性的Vit A代谢产物之一，国内外一些报道表明：RA类化合物具有抑制细胞增殖、诱导 …

1.Recently, all-trans retinoic acid (ATRA) has been used as an antifibrosis drug in many experimental models.近来较多的研究表明全反式维甲酸（ATRA）具有抗纤维化作用。

2.ATRA could inhibit HL60 cell proliferation, and with the increase in drug concentration, the effect of inhibiting the more significant.ATRA明显抑制HL60细胞增殖，并随药物浓度的增加，抑制效果也越显著；

3.Thus, we studied whether maintenance therapy in ALL, like ATRA in APL , may be inducing terminal differentiation of ALL progenitors.像在APL上使用ATRA一样，我们研究的所有维持疗法都可以诱导原生组织分化。

4.Results There were obvious differences in gene expression between human lung cancer cells before and after ATRA treatment.结果在全反式维甲酸诱导前后的细胞之间存在明显的基因表达差异。

5.Cellular chemical staining and transmission electron microscope results also show that ATRA could induce HL60 cells to granulocyte cells.细胞化学染色和透射电镜结果亦表明诱导后的HL60细胞向粒系分化。

6.METHODS CTX-dwas fractionated and purified from Naja naja atra venom by column chromatography and RP-HPLC.方法应用柱层析及RP-HPLC，从眼镜蛇毒粗毒中分离纯化细胞素素（CTX）。

7.After ATRA and chemotherapy treatment, transcript levels gradually decreased to 1030 copies.经过ATRA+化疗治疗后转录本水平又逐渐下降至1030。

8.ConclusionsThe model of ATRA-induced HL60 cells to granulocyte differentiation was successfully established.结论建立了ATRA诱导HL60细胞向粒系分化的完整模型。

9.Objective: To study the anti-proliferation effects of ATRA on MB39 cells and the approach of its action.目的：本文主要探讨ATRA对髓母细胞瘤细胞系MB39细胞增殖生存的影响及其作用途径。

10.OBJECTIVE To purify cytotoxin(CTX) from Naja naja atra venom, and to study its antitumor activity.目的分离纯化眼镜蛇毒细胞毒素，测定其体内外抗癌作用。